Flu-like symptoms Approximately 70% of patients during the first 6 months. during therapy with Rebif may be a typical interferon flu-like proviron buy symptoms (headache, fever, chills, muscle and joint pain, nausea). These symptoms usually are mild, are more common at the beginning of the treatment and decrease with continued treatment. The patient should be informed that if any of these symptoms is strongly expressed or constant, it should inform the doctor. Your doctor may prescribe anti-inflammatory painkillers, or temporarily change the dose. The reactions at the injection site Approximately 30% of patients may be injection-site reactions (redness or paleness of the skin, swelling, skin pallor, pain), which are usually expressed slightly and are reversible. In rare cases, injection site necrosis develops, which usually resolves on its own. Occasionally possible infection of the injection site. The skin in this area can become resilient, edematous, marked tenderness. The reactions of the digestive, nervous, cardiovascular, and others. Systems For more rare side effects associated with interferon beta include diarrhea, loss of appetite, vomiting, insomnia, dizziness, nervousness, rash, vasodilation and palpitation, violations / changes of the menstrual cycle.
Hypersensitivity and allergic reactions severe allergic reactions can occur in exceptional cases. If immediately after the injection, the patient felt shortness of breath which may be accompanied by hives, feeling of weakness or faintness, he should immediately seek medical attention. Laboratory Abnormalities possible abnormal laboratory values, manifested leukopenia, lymphopenia, proviron buy thrombocytopenia, increased levels of hepatic transaminases, especially alanine aminotransferase. These changes are usually small, asymptomatic and reversible.There may be loss of appetite, nausea, vomiting, yellowness.
Reaschii on the part of the endocrine system Interferons can okazyval effect on thyroid function, as in the upward and oppression. These changes may not be accompanied by clinical symptoms, but your doctor may prescribe additional tests. Depression Patients rassyannym sclerosis may develop depression. It is necessary to inform the doctor about any of the above side effects of the drug, including those that are not listed in these instructions. When you save the adverse reactions for a long time or in case of severe adverse reactions at the physician’s discretion may be a temporary reduction in the dose or interrupt treatment. You should not stop treatment or change the dose without a doctor. Interaction with other medicinal products.Specially-designed clinical trials to study the interaction of the drug Rebif ® with other drugs have not been conducted. However, it is known that in humans and animal interferons reduce the activity of cytochrome P-450-dependent liver enzymes. Therefore, caution should be exercised in the appointment of proviron buy in conjunction with drugs that have a narrow therapeutic index, the clearance of which largely depends on the cytochrome P-450 system of the liver, such as antiepileptic drugs and some antidepressants. A systematic study of the interaction of with corticosteroids or was conducted. Data from clinical studies indicate the possibility of getting sick with multiple sclerosis Rebif and corticosteroids or during relapses of the disease. steroids for lungs genotropin pens steroids abuse